Fatty acid may help combat multiple sclerosis

Press release:

The abnormal immune system response that causes multiple sclerosis (MS) by attacking and damaging the central nervous system can be triggered by the lack of a specific fatty acid in fat tissue, according to a new Yale study. The finding suggests that dietary change might help treat some people with the autoimmune disease.

The study was published Jan. 19 in The Journal of Clinical Investigation.

Fat tissue in patients diagnosed with MS lack normal levels of oleic acid, a monounsaturated fatty acid found at high levels in, for instance, cooking oils, meats (beef, chicken, and pork), cheese, nuts, sunflower seeds, eggs, pasta, milk, olives, and avocados, according to the study.

This lack of oleic acids leads to a loss of the metabolic sensors that activate T cells, that mediate the immune system’s response to infectious disease, the Yale team found. Without the suppressing effects of these regulatory T cells, the immune system can attack healthy central nervous system cells and cause the vision loss, pain, lack of coordination and other debilitating symptoms of MS.

When researchers introduced oleic acids into the fatty tissue of MS patients in laboratory experiments, levels of regulatory T cells increased, they found.

“We’ve known for a while that both genetics and the environment play a role in the development of MS,” said senior author David Hafler, William S. and Lois Stiles Edgerly Professor of Neurology and professor of immunobiology and chair of the Department of Neurology. “This paper suggests that one of environmental factors involved is diet.”

Hafler noted that obesity triggers unhealthy levels of inflammation and is a known risk factor for MS, an observation that led him to study the role of diet in MS.

He stressed, however, that more study is necessary to determine whether eating a diet high in oleic acid can help some MS patients.

###

Saige L. Pompura of the Yale School of Medicine is lead author of the study.

Advertisement:

SaleBestseller No. 1
Multiple Sclerosis for Dummies: 2nd Edition
  • Kalb, Rosalind (Author)
  • English (Publication Language)
  • 384 Pages - 04/13/2012 (Publication Date) - For Dummies (Publisher)
Bestseller No. 2
Lokai Multiple Sclerosis Cause Collection Bracelet, Medium
  • Multiple Sclerosis Lokai:┬áMultiple Sclerosis (Ms) Is An Unpredictable, Often Disabling Disease Of The Central Nervous System That Disrupts The Flow Of Information Within The Brain, And Between The Brain And Body. Can Do Ms Delivers Health And Wellness Education Programs To Help Families Living With Ms Thrive
  • Give Back: Lokai Will Donate $1 To Can Do Ms For Each Multiple Sclerosis Lokai Sold In 2020.
  • Stay Humble: The White Bead Is Infused With Water From Mount Everest, The Highest Point On Earth, As A Reminder To Stay Humble.
  • Stay Hopeful: The Black Bead Carries Mud From The Dead Sea, The Lowest Point On Earth, As A Reminder To Always Stay Hopeful.
SaleBestseller No. 3
The Multiple Sclerosis Diet Plan and Cookbook: 101 Easy Anti-Inflammatory Recipes
  • DeSantis MS RD CDN, Noelle (Author)
  • English (Publication Language)
  • 228 Pages - 12/17/2019 (Publication Date) - Rockridge Press (Publisher)
Bestseller No. 4
Living Proof
  • Amazon Prime Video (Video on Demand)
  • Matt Embry, Dr. Ashton Embry, Dr. Terry Wahls (Actors)
  • Matt Embry (Director) - Matt Embry (Writer) - Tyler McLeod (Producer)
  • German, Portuguese, Bulgarian, English, Italian (Playback Language)
  • German, Portuguese, Bulgarian, English, Italian (Subtitles)
SaleBestseller No. 6
Multiple Sclerosis, Fifth Edition: A Guide for the Newly Diagnosed
  • Murray MD, T.Jock (Author)
  • English (Publication Language)
  • 256 Pages - 09/28/2017 (Publication Date) - Demos Health (Publisher)
Bestseller No. 7
MS Warrior Heart Multiple Sclerosis Awareness Month T-Shirt
  • With this MS Awareness design every MS patient will love to show their strenghts to fight MS as a desease similar to cancer and even family members and friends will want to show their support by wearing the orange ribbon band on a tee.
  • Lightweight, Classic fit, Double-needle sleeve and bottom hem
SaleBestseller No. 8
The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles
  • The Wahls Protocol A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Princip Les
  • Wahls M.D., Terry (Author)
  • English (Publication Language)
  • 560 Pages - 12/30/2014 (Publication Date) - Avery (Publisher)
Bestseller No. 9
Life With Multiple Sclerosis
  • Amazon Prime Video (Video on Demand)
  • Kevin J. Lindenmuth (Actor)
  • Kevin J. Lindenmuth (Director)
  • English (Playback Language)
  • English (Subtitle)
Bestseller No. 10
Overcoming Multiple Sclerosis: The Evidence-Based 7 Step Recovery Program
  • Jelinek, George (Author)
  • English (Publication Language)
  • 476 Pages - 10/01/2016 (Publication Date) - Allen & Unwin (Publisher)

I get commissions for purchases made through links on this website. As an Amazon Associate I earn from qualifying purchases.